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Camostat Mesylate

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arudiangem@*.com

Aug 02 2020, 6:24 am

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COVID-19 Insights. An Invitro VIRAL BLOCKER Camostat Mesylate

Links to the news

Acute MI incidence reduced during the lockdown. It will increase once the lockdown lifted.
https://www.nejm.org/doi/full/10.1056/NEJMc2015630
Infection can spread by aerosol
https://www.nejm.org/doi/full/10.1056/NEJMc2009324
CDC thinks that the virus spreads more from humans to humans than the fomites.
https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/how-covid-spreads.html


Links to the studies and medical concepts

The Impact of Camostat Mesylate on COVID-19 Infection (CamoCO-19)
From https://clinicaltrials.gov/ct2/show/NCT04321096
Study that proves Camostat Mesylate blocks viral (SARS-COV-2) entry into the cells
https://www.eurekalert.org/pub_releases/2020-03/dpp-pso030520.php

How serine proteases cut the proteins
https://en.wikipedia.org/wiki/Serine_protease

Camostat mesylate
https://en.wikipedia.org/wiki/Camostat
Camostat invitro study
https://pubmed.ncbi.nlm.nih.gov/32142651/
Camostat dosage
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188520/
Camostat trials
https://clinicaltrials.gov/ct2/show/NCT04321096
https://clinicaltrials.gov/ct2/show/NCT04353284

Spike protein priming
https://link.springer.com/chapter/10.1007/978-3-319-75474-1_4

Six helices for the S2 subunit of the Spike protein
https://www.researchgate.net/figure/The-fusion-core-structureThe-fusion-core-is-a-six-helix-bundle-with-three-HR2-helices_fig3_23986117

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